2.11 Antifibrinolytic drugs and haemostatice

Tranexamic Acid
  • Tablets 500mg (£6.73 = 60 pack)
  • Injection 500mg in 5ml
  • Mouthwash 5%, 300ml (unlicensed preparation)

Indications

  • Local fibrinolysis
  • Menorrhagia
  • Hereditary angioedema
  • Epistaxis

Dose

  • Local fibrinolysis, 1–1.5g (or 15–25mg/kg) 2–3 times daily
  • Menorrhagia (initiated when menstruation has started), 1g 3 times daily for up to 4 days; maximum 4g daily
  • Hereditary angioedema, 1–1.5g 2–3 times daily
  • Epistaxis, 1g 3 times daily for 7 days
Aprotinin
  • Injection 500, 000 KI units in 50ml
Etamsylate
  • Injection 250mg in 2ml (unlicensed preparation)

Notes

  1. For use within Plymouth Hospitals NHS Trust

 

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