5.1.3 Tetracyclines

Oxytetracycline
  • Tablets 250mg (£1.09 = 28 tablets)

Indications

Doxycycline
  • Capsules 50mg (£2.38 = 28 pack), 100mg (£1.52 = 8 pack)
  • Dispersible tablets sugar free (£4.91 = 8 tablets)
  • Efracea® modified release capsules 40mg (£15.98 = 28 capsules)

Indications

Notes

  1. COVID-19: Doxycycline should NOT be used in the management of confirmed or suspected COVID-19 infection within primary care, unless there are additional indications for which its use remains appropriate. For more information, see the CAS alert (issued 28 January 2021)
  2. Doxycycline 40mg (Efracea) is included for the treatment of rosacea
  3. Dispersible tablets are considerably more expensive than capsules and should be reserved for use only in individuals who are unable to swallow capsules
Lymecycline
  • Capsules 408mg (£4.33 = 28 capsules)

Indications

Demeclocycline hydrochloride
  • Capsules 150mg (£200.66 = 28 capsules)

Notes

  1. Demeclocycline is not used for the treatment of infection, but is used in the management of inappropriate secretion of antidiuretic hormone.
Tigecycline
  • I/V infusion 50mg vial
Minocycline

Following national guidance from NHS England, minocycline is not recommended for use for the treatment of acne due to an increased risk of adverse effects such as drug induced lupus, skin pigmentation and hepatitis. Click here for more information. Prescribers should not initiate minocycline for acne for any new patient.

 

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