5.1.1 Penicillins

5.1.1 Benzylpenicillin and phenoxymethylpenicillin

Benzylpenicillin sodium

• Injection 600mg vial (£6.08 = 2 vials)

Indications

• Suspected meningococcal disease

Phenoxymethylpenicillin

• Tablets 250mg (£0.93 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£4.28, £5.23 = 100ml)

Indications

• Acute sore throat
• Acute sinusitis
• Dental abscess

Benzathine benzylpenicillin

• Injection 2,400,00 units (unlicensed preparation)

Notes

1. Benzathine benzylpenicillin is included for the treatment of syphilis infection only

5.1.1.2 Penicillinase-resistant penicillins

Flucloxacillin

• Capsules 250mg, 500mg (£1.42, £2.34 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£6.37, £31.71 = 100ml)

Indications

• Impetigo
• Eczema
• Cellulitis
• Leg ulcers
• Lacerated wounds

5.1.1.3 Broad-spectrum penicillins

Amoxicillin

• Capsules 250mg, 500mg (£1.05, £1.08 = 21 pack)
• Oral suspension 125mg/5ml, 250mg/5ml (£01.40, £1.59 = 100ml)
• Powder for solution for injection vials 250mg, 500mg, 1g (£1.96 = 1g vial)

Indications

• Acute otitis media
• Acute cough, acute bronchitis
• Acute exacerbations of COPD
• Community acquired pneumonia - with clarithromycin
• UTI in pregnancy (specialist use)
• Eradication of H. pylori
• Chlamydia trachomatis - (second line) (pregnancy, breast-feeding patients)
• Lyme disease
• Pericoronitis
• Dental abscess

Co-amoxiclav

• Tablets 250/125, 500/125 (£1.67, £2.31 = 21 pack)
• Oral suspension^SF 125/31mg/5ml, 250/62mg/5ml (£1.65, £1.67 = 100ml)
• Injection 500/100, 1000/200
• Oral suspension 400/57mg/5ml

Indications

• Acute otitis media
• Acute sinusitis
• Acute exacerbations of COPD
• Upper UTI in children - (first line)
• Facial cellulitis - (first line)
• Bites (animal or human) - (first line)
• Lacerated wounds - (first line)

5.1.1.4 Antipseudomonal penicillins

Tazocin®

• Injection piperacillin 2g / tazobactam 250mg
• Injection piperacillin 4g / tazobactam 500mg

Timentin®

• Injection ticarcillin 3g / clavulanic acid 200mg

Notes

1. For use within Plymouth Hospitals NHS Trust

5.1.1.5 Mecillinams

Pivmecillinam

• Tablets 200mg (£5.40 = 10 pack)

Indications

• Uncomplicated UTI in adults
• Community multi-resistant UTIs

Home > Formulary > Chapters > 5. Infections > 5.1 Antibacterial drugs > 5.1.1 Penicillins

• First line
• Second line
• Specialist
• Hospital