5.1.1 Penicillins

5.1.1 Benzylpenicillin and phenoxymethylpenicillin

Benzylpenicillin sodium

• Injection 600mg vial (£5.46 = 2 vials)

Indications

• Suspected meningococcal disease

Phenoxymethylpenicillin

• Tablets 250mg (£0.97 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£14.73, £14.66 = 100ml)

Indications

• Acute sore throat
• Dental abscess

Benzathine benzylpenicillin

• Injection 2,400,00 units (unlicensed preparation)

Notes

1. Benzathine benzylpenicillin is included for the treatment of syphilis infection only

5.1.1.2 Penicillinase-resistant penicillins

Flucloxacillin

• Capsules 250mg, 500mg (£1.23, £1.99 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£4.85, £26.04 = 100ml)

Indications

• Impetigo
• Eczema
• Cellulitis
• Leg ulcers
• Lacerated wounds

5.1.1.3 Broad-spectrum penicillins

Amoxicillin

• Capsules 250mg, 500mg (£0.97, £1.26 = 21 pack)
• Oral suspension 125mg/5ml, 250mg/5ml (£0.97, £1.10 = 100ml)
• Injection 250mg, 500mg, 1g vials (£1.96 = 1g vial)

Indications

• Acute otitis media
• Acute rhinosinusitis
• Acute cough, acute bronchitis
• Acute exacerbations of COPD
• Community acquired pneumonia - with clarithromycin
• UTI in pregnancy (specialist use)
• Eradication of H. pylori
• Chlamydia trachomatis (second line) (pregnancy, breast-feeding patients)
• Lyme disease
• Pericoronitis
• Dental abscess

Co-amoxiclav

• Tablets 250/125, 500/125 (£1.66, £1.73 = 21 pack)
• Oral suspension^SF 125/31mg/5ml, 250/62mg/5ml (£1.84, £1.83 = 100ml)
• Injection 500/100, 1000/200
• Oral suspension 400/57mg/5ml

Indications

• Acute otitis media
• Acute rhinosinusitis
• Acute exacerbations of COPD
• Upper UTI in children (first line)
• Facial cellulitis (first line)
• Bites (animal or human) (first line)
• Lacerated wounds (first line)

5.1.1.4 Antipseudomonal penicillins

Tazocin®

• Injection piperacillin 2g / tazobactam 250mg
• Injection piperacillin 4g / tazobactam 500mg

Timentin®

• Injection ticarcillin 3g / clavulanic acid 200mg

Notes

1. For use within Plymouth Hospitals NHS Trust

5.1.1.5 Mecillinams

Pivmecillinam

• Tablets 200mg (£4.50 = 10 pack)

Indications

• Uncomplicated UTI in adults
• Community multi-resistant UTIs

Home > Formulary > Chapters > 5. Infections > 5.1 Antibacterial drugs > 5.1.1 Penicillins

• First line
• Second line
• Specialist
• Hospital