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Page last updated:
25 October 2024
This guidance applies to hypertension in adults.
For women considering pregnancy or who are pregnant or breastfeeding, manage hypertension in line with the recommendations on the Management of hypertension in pregnancy
The information below is based on the following NICE guidelines:
Clinical Referral Guidance
This guidance is based on NICE NG136
Ensure that devices are properly validated, maintained and regularly recalibrated. A list of validated devices is available on the British and Irish Hypertension Society website.
Confirm diagnosis of hypertension using 24 hour ABPM or HBPM.
Carry out investigations for target organ damage and assess cardiovascular risk using a formal cardiovascular risk assessment tool.
Refer for same-day specialist assessment if there are:
If there are no symptoms or signs indicating same-day specialist assessment, assess for target organ damage as soon as possible:
Refer to clinical referral guidance: South Devon / West Devon
If hypertension is not diagnosed, measure the person's clinic BP at least every 5 years subsequently, and consider measuring it more frequently if the person's clinic BP is close to 140/90 mmHg.
Type 1 and type 2 diabetes
Measure BP at least annually in an adult with type 1 or 2 diabetes without previously diagnosed hypertension or renal disease. Offer and reinforce preventive lifestyle advice
Offer advice on healthy lifestyle changes to reduce cardiovascular risk
Clinic BP must be used to calculate cardiovascular risk.
Use the QRISK assessment tool to assess cardiovascular disease risk for the primary prevention of cardiovascular disease up to and including age 84 years.
Do not use the risk assessment tool for patients with established cardiovascular disease.
Other drugs that reduce cardiovascular risk must also be considered; this includes lipid-lowering therapies (see Management of Lipids) and antiplatelet therapy for secondary prevention of cardiovascular disease.
Routine use of aspirin 75mg for primary prevention is not recommended locally.
Encourage healthy lifestyle changes whether or not people choose to start antihypertensive drug treatment.
NICE has developed a patient decision aid on options for controlling BP.
Use clinical judgement for people with frailty or multimorbidity
Clinic BP 140/90 to 159/99mmHg and subsequent ABPM or HBPM average 135/85 to 149/94mmHg
Over 80 years of age with clinic BP over 150/90mmHg, consider starting antihypertensive drug treatment.
Under 80 years discuss starting antihypertensive drug treatment with people who have one or more of the following:
Under 60 years of age with 10-year risk of cardiovascular disease below 10%, consider antihypertensive drug treatment. Encourage healthy lifestyle changes.
Under 40 years of age, consider seeking specialist evaluation of secondary causes of hypertension and assessment of long-term benefits and risks of antihypertensive drug treatment.
Clinic BP 160/100mmHg or higher but less than 180/120mmHg and subsequent ABPM or HBPM average of 150/95mmHg or higher
Offer antihypertensive drug treatment to adults of any age. Use clinical judgement for people with frailty or multimorbidity.
Under 40 years of age, consider seeking specialist evaluation of secondary causes of hypertension and assessment of long-term benefits and risks of antihypertensive drug treatment.
Offer people with isolated systolic hypertension (systolic BP 160mmHg or higher) the same treatment as people with both raised systolic and diastolic BP.
All targets refer to clinic BP measurements
For people identified as having 'white-coat effect' hypertension, consider ABPM or HBPM in addition to clinic BP measurements. Aim for a target average BP taken during usual waking hours of:
Use clinical judgement for people with frailty or multimorbidity.
Treat to a BP target based on standing BP for people with significant postural drop or symptoms of postural hypotension.
Use the same BP targets for people with and without cardiovascular disease.
Use clinical judgement for adults with frailty or multimorbidity.
Person under 80 with: | Clinic BP target | Target systolic BP range |
hypertension (with or without type 2 diabetes) – if CKD see below | Below 140/90 | None specified |
type 1 diabetes plus ACR less than 70mg/mmol | Below 140/90 | 120 to 139 |
type 1 diabetes plus ACR of 70mg/mmol or more | Below 130/80 | 120 to 129 |
chronic kidney disease plus ACR less than 70mg/mmol | Below 140/90 | 120 to 139 |
chronic kidney disease plus ACR of 70mg/mmol or more | Below 130/80 | 120 to 129 |
ACR = albumin to creatinine ratio
Use clinical judgement for adults with frailty or multimorbidity.
Person aged 80 and over with: | Clinic BP target | Target systolic BP range |
hypertension (with or without type 2 diabetes) – if CKD see below | Below 150/90 | None specified |
type 1 diabetes (regardless of ACR) | Below 150/90 | None specified |
chronic kidney disease plus ACR less than 70mg/mmol | Below 140/90 | 120 to 139 |
chronic kidney disease plus ACR of 70mg/mmol or more | Below 130/80 | 120 to 129 |
ACR = albumin to creatinine ratio
Target systolic BP ranges for patients with type 1 diabetes or with CKD are taken from NICE NG17 and NICE NG203 respectively.
Non-pharmacological lifestyle interventions should be offered initially and then periodically to people undergoing assessment or treatment for hypertension.
Non-pharmacological measures; weight reduction, reduced salt intake, reduced fat intake, limited alcohol consumption, aerobic exercise and increased fruit and vegetable consumption are effective in lowering blood pressure (level 1 evidence).
Weight reduction
Recommendation: Maintain BMI 20-25
Expected SBP reduction: 5-10mmHg per 10kg weight loss
DASH eating plan (link)
Dietary sodium restriction
Physical activity
Alcohol moderation
Alone or in combination these interventions can reduce the need for drug therapy and enhance the effect of antihypertensive agents. A favourable effect on cardiovascular outcome is assumed, but not proven.
To reduce overall cardiovascular risk, patients should stop smoking, reduce total fat and saturated fat intake and increase consumption of monounsaturated fats and oily fish.
Device-guided breathing (Resperate)
Results from randomised trials involving Resperate are contradictory, although it would appear there may be a small reduction in BP when the device is used over an 8 week period. The long-term effectiveness of Resperate is not known.
The British Hypertension Society (BHS) advises that there is currently insufficient evidence to recommend the use of Resperate devices.
In the absence of long-term efficacy data involving patient-centred outcomes Resperate devices should not be prescribed on NHS prescriptions. Patients wishing to use Resperate may purchase the device privately.
Annual review
Check BP, discuss lifestyle, symptoms and medication. Encourage adherence to treatment.
Women of child-bearing potential
For women considering pregnancy or who are pregnant or breastfeeding, manage hypertension in line with the guidance on the Management of hypertension in pregnancy.
Patients with cardiovascular disease
For people with hypertension and cardiovascular disease, follow treatment recommendations specific to their condition (e.g. heart failure, secondary prevention of myocardial infarction) first. If their BP remains uncontrolled, offer antihypertensive drug treatment in line with the recommendations in this section.
Type 2 diabetes
Follow recommendations below. For patients with type 2 diabetes and CKD, refer to the guidance for CKD below.
If the patient is receiving antihypertensive drug treatment when type 2 diabetes is diagnosed, review BP control and medications used. Make changes only if there is poor control or if current drug treatment is not appropriate because of microvascular complications or metabolic problems.
The NICE NG136 visual summary has a flow chart of steps 1-4. First-line formulary options and cross-references to formulary drug entries and additional notes are provided below.
NICE patient decision aid on options for controlling BP
Patients with type 2 diabetes of any age or family origin:
Patients without type 2 diabetes:
Aged 55 years or over, or are of Black African or African-Caribbean family origin of any age:
Notes
If blood pressure is not controlled on Step 1 treatment, discuss adherence, add a second drug:
Step 1 treatment ACE inhibitor or ARB, add:
Step 1 treatment calcium channel blocker, add:
Notes
Review medication to ensure step 2 treatment is at optimal or best tolerated doses and discuss adherence
If treatment with 3 drugs is required offer a combination of:
Notes
Clinic BP greater than 140/90mmHg despite optimal tolerated doses of drugs described in Step 3. Confirm elevated BP reading using ambulatory or home BP recordings, assess for postural hypotension and discuss adherence.
Seek specialist advice if the patient is receiving 3 drugs and there are complications. If there are no complications, add 4th drug:
Notes
Type 1 diabetes
Provide information to adults with type 1 diabetes on the potential for lifestyle changes to improve BP control and associated outcomes, and offer assistance in achieving their aims in this area.
If there is kidney damage (including microalbuminuria)
Do not offer a combination of renin-angiotensin system antagonists to people with CKD.
When prescribing calcium channel blockers, only use long-acting preparations.
CKD and hypertension (see above for patients with type 1 diabetes)
ACR of 30mg/mmol or less (ACR categories A1 and A2):
ACR over 30mg/mmol (ACR category A3 or above)
Do not offer a combination of renin-angiotensin system antagonists to people with CKD.