Formulary

8.3.2 Progestogens

First Line
Second Line
Specialist
Hospital Only
Medroxyprogesterone acetate
  • Tablets 5mg, 10mg (£1.23 = 5mg x 10)
  • Tablets 100mg, 200mg, 400mg (£49.94 = 100mg x 100)

Indications and dose

  • Oral: 2.5–10mg daily for 5–10 days beginning on day 16 to 21 of cycle, repeated for 2 cycles in dysfunctional uterine bleeding and 3 cycles in secondary amenorrhoea
  • Oral: mild to moderate endometriosis, 10mg 3 times daily for 90 consecutive days, beginning on day 1 of cycle.
  • Doses used for the management of carcinoma are much higher – refer to specialist for guidance.
Megestrol acetate
  • Tablets 160mg (£19.52 = 30 tablets)