Important: Drugs in this section should be used only by doctors with anaesthetic training and should not be administered parenterally unless resuscitation equipment is available.

Bupivacaine

Bupivacaine hydrochloride

• Solution for injection 2.5mg in 1ml (0.25%), 25mg in 10ml ampoule
• Solution for injection 5mg in 1ml (0.5%), 50mg in 10ml ampoule
• Solution for injection 75mg in 10ml (0.75%) ampoule
• Solution for injection 300mg in 10ml (3%) ampoule (unlicensed) Pain Clinic only
• 312.5mg in 250ml (0.125% in NaCl 0.9%) (unlicensed) for epidural use
• 625mg in 500ml (0.125% in NaCl 0.9%) (unlicensed) for epidural/perineural block infusion
• 835mg in 500ml (0.167% in NaCl 0.9%) (unlicensed) for epidural/perineural block infusion

Bupivacaine with glucose

• Bupivacaine 20mg (0.5%) with glucose 320mg in 4ml spinal injection

Bupivacaine with adrenaline

• Solution for injection 25mg (0.5%) with adrenaline 50 micrograms (1 in 200,000) in 10ml ampoule
• Solution for injection 50mg (0.5%) with adrenaline 50 micrograms (1 in 200,000) in 10ml ampoule

Bupivacaine with fentanyl

• 0.1% with fentanyl 2 micrograms in 1ml 250ml, 500ml for epidural infusion
• 0.1% with fentanyl 1mg in 1ml, 500ml (unlicensed) for epidural infusion

Bupivacaine with diamorphine

• 0.167% with diamorphine 50 micrograms in 1ml, 500ml (unlicensed) for epidural infusion
• Diamorphine 5mg and 10mg injection: supplies will be unpredictable for the foreseeable future (DSHC, March 2020). Contact the pharmacy department before prescribing to determine whether there is stock available
  

Chloroprocaine

Chloroprocaine hydrochloride

• Solution for injection 10mg in 1ml, 5ml ampoule

Levobupivacaine

Levobupivacaine

• Injection 2.5mg in 1ml (0.25%), 10ml ampoule
• Injection 2.5mg in 1ml (0.25%), 10ml ampoule overwrapped
• Injection 5mg in 1ml (0.5%), 10ml ampoule
• Injection 5mg in 1ml (0.5%), 10ml ampoule overwrapped

Lidocaine

Lidocaine preparations used for local anaesthesia, listed elsewhere in the formulary:

• Instillagel, see section 18.4 Catheter accessories
• Lidocaine 700mg (5% w/w) medicated plaster and Emla Cream see section 10.3.3 Topical analgesia and capsaicin

Lidocaine hydrochloride

• Solution for injection 20mg in 2ml (1%) (£0.35 = 1 ampoule)
• Solution for injection 50mg in 5ml (1%) (£0.40 = 1 ampoule)
• Solution for injection 100mg in 5ml (2%) (£0.44 = 1 ampoule)
• Spray sugar free 10mg/dose (£6.29 = 50ml bottle)
• Ointment 5% (15g)
• Injection 50mg in 10ml (0.5%) vial
• Injection 200mg in 20ml (1%) ampoule
• Injection 200mg in 20ml (1%) vial preserved
• Injection 100mg in 5ml (2%) prefilled syringe
• Injection 400mg in 20ml (2%) ampoule
• Topical solution 4% (30ml) (unlicensed)

Lidocaine with adrenaline

• Solution for injection 10mg in 1ml (1%) with adrenaline 5 micrograms in 1ml (1 in 200,000) (£1.93 = 20ml vial)
• Dental solution for injection cartridge 44mg in 2.2ml (2%) with adrenaline 27.5 micrograms in 2.2ml (1 in 80,000) (£0.69 = 1 cartridge)
• Injection 200mg (1%) with adrenaline 100 micrograms (1 in 200,000) in 20ml vial preserved
• Injection 400mg (2%) with adrenaline 100 micrograms (1 in 200,000) in 20ml vial preserved

Lidocaine with glucose

• IV infusion 1g (0.2%) with glucose 25g (5%) in 500ml

Lidocaine 5% with Phenylephrine 0.5%

• Nasal spray (2.5ml)

Mepivacaine

Mepivacaine hydrochloride

• Solution for injection cartridge 66mg in 2.2ml (£0.71 = 1 cartridge)

Prilocaine

Prilocaine with felypressin

(30mg in 1ml (3%) with 0.03 units in 1ml)

• Solution for injection self aspirating cartridge 2.2ml

Prilocaine

• Injection 50mg (0.5%) 10ml ampoule unpreserved (unlicensed)
• Injection 10mg in 1ml (1%) 50ml multi-dose vial

Notes

1. For Bier's Block 0.5% prilocaine must be used.

Ropivacaine

Ropivacaine

• Injection 7.5mg in 1ml, 10ml ampoule

Tetracaine

Tetracaine

• 4% gel 1.5g (£1.08)