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Constipation is characterised by difficult or painful defaecation, and is associated with infrequent bowel evacuations, and hard, small faeces.
It is a very common cause of distress in palliative care patients. It is better to prevent it than to wait until treatment is needed.
When opioids are commenced it is almost always appropriate to start a laxative. Relatively high doses of laxative may be needed; the dose should be increased as the dose of opioid increases.
Constipation in patients with progressive disease is usually multifactorial.
Causes to consider
Effects of chronic constipation
Anticipate constipation; ask about previous bowel function, medications and other possible causative factors.
Exclude malignant intestinal obstruction. Abdominal palpation, auscultation and digital rectal examination are needed for proper assessment of constipation.
Investigations may be needed to guide treatment e.g. plain abdominal x-ray, calcium level to exclude hypercalcaemia.
Most palliative care patients are too debilitated to tolerate the dietary measures needed to combat constipation and to tolerate laxatives such as bulking agents. High fluid intake, fruit and fruit juice (especially prune juice) all help.
Laxative doses should be increased until constipation is controlled and may need to be higher than in other patients
See section 1.6 Laxatives