These preparations are used here, but are listed elsewhere in the formulary:
Hydralazine
- Tablets 25mg, 50mg (£8.74 = 50mg four times a day)
- Powder for solution for injection ampoules 20mg
Indications
Dose
- Heart failure (initiated in hospital), 25mg 3–4 times daily, increased every 2 days if necessary; usual maintenance dose 50–75mg 4 times daily
- Hypertension, 25mg 3–4 times daily, increased every 2 days if necessary; usual maintenance dose 50–75mg 4 times daily
Bosentan
Indication
- Treatment of digital ulceration (DU) in systemic sclerosis in adults
Notes
- NHS England (NHSE) will commission sildenafil and bosentan for patients requiring treatment of digital ulceration in systemic sclerosis in adults, in accordance with the criteria outlined in the NHSE Commissioning Policy
- Patients requiring treatment with bosentan will be referred by their usual consultant rheumatologist for an opinion from a specialised rheumatology centre
Sodium nitroprusside
- Solution for infusion vials 50mg/2ml (unlicensed preparation)