4.12 Oligonucleotide inhibitors

Inotersen

• Solution for injection in pre-filled syringes 284mg in 1.5ml

Notes

1. NICE HST9: Inotersen (Tegsedi) is recommended as an option for treating stage 1 and stage 2 polyneuropathy in adults with hereditary transthyretin amyloidosis (May 2019)

Patisiran sodium

• Concentrate for solution for infusion vials 10mg in 5ml

Notes

1. NICE HST10: Patisiran (Onpattro) is recommended as an option for treating hereditary transthyretin amyloidosis in adults with stage 1 and stage 2 polyneuropathy (August 2019)

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