Formulary

9.1.6 Drugs used in neutropenia

First Line
Second Line
Specialist
Hospital Only
Filgrastim
  • Neupogen injection 30 million units (300 micrograms) in 1ml vial
  • Neupogen injection 30 million units (300 micrograms) in 0.5ml pre-filled syringe
  • Accofil injection 30 million units (300 micrograms) in 0.5ml pre-filled syringe
  • Accofil injection 48 million units (480 micrograms) in 0.5ml pre-filled syringe
  • Zarzio injection 30 million units (300 micrograms) in 0.5ml pre-filled syringe
  • Zarzio injection 48 million units (480 micrograms) in 0.5ml pre-filled syringe

Notes

  1. Prescribe by brand. Filgrastim is available as Neupogen and the biosimilar products Accofil and Zarizo. A biosimilar medicine is a biological medicine that is highly similar and clinically equivalent (in terms of quality, safety, and efficacy) to an existing biological medicine however they cannot be considered generic equivalents of the originator biological medicine. Because they are not identical, biological medicines must be prescribed by brand. The decision which brand to prescribe rests with the responsible clinician in consultation with the patient. Automatic substitution of brands at the point of dispensing is not appropriate for biological medicines.
Lenograstim
  • Pre-filled syringe 13.4 million-unit (105 micrograms), 33.6 million-unit (263 micrograms)
Pegfilgrastim
  • Pre-filled syringe 6mg/0.6ml