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April 2025: Updated cellulitis and erysipelas guidance
Cellulitis and erysipelas
Updates include:
Guidance has been expanded to include erysipelas (recommendations and treatment options are the same as for cellulitis).
Additional information has been added to support assessment, re-assessment, and referral.
Treatment recommendations for adults aged 18 years and over have been amended, these include:
Antibiotic course durations have been reduced to 5-7 days
Two additionalblue
(second line) options have been added:
erythromycin (for use in pregnancy)
doxycycline
Clindamycin has been removed
as a treatment option (previously S&W only)
Recommendations for “facial cellulitis” have been amended to “infection near the eyes or nose”, and dual therapy with clarithromycin plus metronidazole has been added as a blue (second line) option for those patients.
Treatment recommendations for those under 18 years of age have been added, these include:
Flucloxacillin as a green (first line) treatment option
Three blue (second line) options:
co-amoxiclav
clarithromycin
erythromycin (for use in pregnancy)
For infection near the eyes or nose:
Co-amoxiclav as a green (first line) option
Clarithromycin plus metronidazole (if anaerobes suspected) as a blue (second line) option.