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These guidelines cover the referral and management for adults with central sensitivity syndrome / fibromyalgia.
Two key considerations here are timely diagnosis and early appropriate management. This should result in the majority of these patients being managed successfully in primary care.
Fibromyalgia is one of several overlapping functional disorders which are sometimes termed central sensitivity syndrome . A consistent diagnostic approach within the health care community should help avoid patients receiving unhelpful multiple diagnoses. Overlapping syndromes include CFS/ME, Functional neurological disorder (FND) and Medically Unexplained Syndrome (MUS).
These guidelines should facilitate management in primary care and help referral of the small number of patients who may need more intensive specialist input.
Patients typically present with multiple symptoms including widespread pain, post-exertional malaise and non-refreshing sleep pattern lasting for at least 3 months. Cognitive and other somatic symptoms are also evaluated in the 2010 ACR diagnostic criteria.
Initial assessment to exclude other infective, inflammatory, metabolic or endocrine causes.
Examination as clinically indicated. This may include:
If fatigue dominates pain in clinical presentation, patient may be more suitable for community Chronic Fatigue Syndrome service (referral guidelines can be found here)
If patient is presenting with non-specific/mechanical low back pain not attributed to a serious pathology, then current local guidelines should be followed.
Please consider the following investigations to exclude other diagnoses, for example (but not limited to):
• Please see Investigations | Diagnosis | Chronic pain | CKS | NICE for further details.
Diagnosis of Fibromyalgia/ Central Sensitivity Syndrome confirmed/anticipated – low risk
The majority of Fibromyalgia diagnoses will be made in Primary Care.
Guidance from or referral to appropriate specialist with suitable priority (e.g. Rheumatologist, Endocrinologist, Psychiatrists) if:
It is expected that there is closure on the need for further investigation and opinion before considering referral to the pain clinic.
Consider early referral to Plymouth Pain Management Centre if:
All referrals must include:
e-Referral Service Selection
Refer to Pain Management
This guideline has been signed off on behalf of NHS Devon.
Publication date: February 2017
Updated: January 2024