Formulary

8.4.12 Vinca alkaloids

First Line
Second Line
Specialist
Hospital Only

Vinblastine, vincristine, vindesine and vinorelbine injections are for intravenous administration only. Inadvertent intrathecal administration can cause severe neurotoxicity, which is usually fatal.

  • See individual trust policies for further details.
Vinblastine sulphate
  • Solution for injection vials 10mg/10ml (intravenous administration only)
Vincristine sulphate
  • Solution for injection vials 1mg/1ml, 2mg/2ml (intravenous administration only)
Vindesine sulphate
  • Powder for solution for injection vials 5mg (intravenous administration only)
Vinorelbine
  • Capsules 20mg, 30mg, 80mg
  • Solution for infusion vials 10mg/1ml, 50mg/5ml (intravenous administration only)
Vinflunine
  • NICE TA272: Vinflunine (Javlor) is not recommended within its marketing authorisation for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tract that has progressed after treatment with platinum-based chemotherapy (January 2013).