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Chapter 5: Infections
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Principles of antibacterial treatment
Upper respiratory tract infections
Lower respiratory tract infections
Acute exacerbation of bronchiectasis (non-cystic fibrosis)
Urinary tract infections (UTI)
Gastro-intestinal tract infections
Genital tract infections
Skin and soft tissue infections
Eye infections
Oral and dental infections
Lyme disease guidance
Meningitis guidance
Methicillin Resistant Staphylococcus Aureus (MRSA) guidance
COVID-19 treatments for patients who do not require hospitalisation
5.1 Antibacterial drugs
5.2 Antifungal drugs
5.3 Antiviral drugs
5.4 Antiprotozoal drugs
5.5 Anthelmintics
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5.2.1 Triazole antifungals
First Line
Second Line
Specialist
Hospital Only
Fluconazole
- Capsules 150mg (£0.72 = 1 capsule)
- Capsules 50mg (£0.86 = 7 capsules)
- Intravenous infusion 2mg/ml, 25ml bottle, 100ml bottle
Indications
Itraconazole
- Capsules 100 mg (£6.34 = 15 capsules)
- Oral solution sugar free 50mg/5ml (£65.95 = 150ml)
- Concentrate for intravenous infusion 250mg/25ml
Indications
Isavuconazole
- Capsules 100mg
- Powder for concentrate for solution for infusion 200mg vial
Posaconazole
- Oral suspension 40mg/ml
- Gastro-resistant tablets 100mg
- Intravenous infusion 300mg
Notes
- Tablets not licensed for oropharyngeal candidiasis
- Where possible, tablets should be used in preference to the suspension because the tablets have a higher bioavailability; the suspension is not interchangeable with the tablets on a milligram-for-milligram basis
Voriconazole
- Tablets 50mg, 200mg
- Intravenous infusion 200mg
