Formulary

Management of asymptomatic bacteriuria (ASB)

First Line
Second Line
Specialist
Hospital Only

Asymptomatic bacteriuria is:

  • not routinely screened for, or treated, in non-pregnant women, men, children and young people
  • routinely screened for*, and treated with antibiotics, in pregnant women because it is a risk factor for pyelonephritis and premature delivery

Screen for asymptomatic bacteriuria on first antenatal visit by sending urine for culture. If asymptomatic bacteriuria is found send a second urine sample for culture.

  • In the instance of positive test result, a summary of actions taken or next steps should be communicated clearly to the patient’s GP.

If the second urine culture confirms asymptomatic bacteriuria (growth of same organism), then offer an immediate antibiotic prescription to pregnant women with asymptomatic bacteriuria, checking any previous urine culture, susceptibility results, and antibiotic prescribing. Please see Pregnant women ≥12 years with UTI (lower) for antibiotic recommendations.

Following any positive culture and treatment, a repeat urine sample to confirm clearance is recommended. Those who have a recurrent episode require review in secondary care.

*UK National Screening Committee (UK NSC, 2020) states that population screening for asymptomatic bacteriuria in pregnant women is not recommended, however it is supported by local maternity specialists and the Saving Babies’ Lives Care Bundle (NHS England, 2023) to reduce preterm birth, the chance of acute pyelonephritis, and neonatal low birthweight.