5.1.1 Benzylpenicillin and phenoxymethylpenicillin

Benzylpenicillin sodium

• Powder for solution for injection vial 600mg (£5.89 = 2 vials)

Indications

• Suspected meningococcal disease

Phenoxymethylpenicillin

• Tablets 250mg (£2.03 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£7.30, £7.35 = 100ml)

Indications

• Acute sore throat
• Acute sinusitis
• Dental abscess

Benzathine benzylpenicillin

• Powder and solvent for suspension for injection vial 2,400,00 units (unlicensed preparation)

Notes

1. Benzathine benzylpenicillin is included for the treatment of syphilis infection only

5.1.1.2 Penicillinase-resistant penicillins

Flucloxacillin

• Capsules 250mg, 500mg (£1.92, £2.01 = 28 pack)
• Oral solution 125mg/5ml, 250mg/5ml (£2.85, £3.28 = 100ml)

Indications

• Impetigo
• Eczema
• Cellulitis
• Leg ulcers
• Lacerated wounds

5.1.1.3 Broad-spectrum penicillins

Amoxicillin

• Capsules 250mg, 500mg (£1.30, £1.57 = 21 pack)
• Oral suspension 125mg/5ml, 250mg/5ml (£1.65, £1.88 = 100ml)
• Powder for solution for injection vials 250mg, 500mg, 1g (£1.92 = 1g vial)

Indications

• Acute otitis media
• Acute cough, bronchitis
  • Adults aged 18 years and over - (second line)
  • Children and young people under 18 years - (first line)
• Acute exacerbation of bronchiectasis (non-cystic fibrosis)
• Acute exacerbations of COPD
• Community acquired pneumonia
• Pregnant women ≥12 years with UTI (lower) - (second line)
• Catheter-associated UTI - (specialist input)
  • Non-pregnant women and men aged 16 years and over with no upper UTI symptoms
  • Children and young people aged 3 months to 16 years
• Recurrent UTI in non-pregnant women - (second line) (off label)
• Eradication of H. pylori
• Chlamydia trachomatis - (second line) (pregnancy)
• Lyme disease
• Pericoronitis
• Dental abscess

Co-amoxiclav

• Tablets 250mg/125mg, 500mg/125mg (£2.16, £3.39 = 21 pack)
• Oral suspension sugar free 125mg/31mg/5ml, 250mg/62mg/5ml (£1.99, £1.90 = 100ml)
• Powder for solution for injection 500mg/100mg, 1000mg/200mg
• Oral suspension sugar free 400mg/57mg/5ml

Indications

• Acute otitis media
• Acute sinusitis
• Acute exacerbation of bronchiectasis (non-cystic fibrosis)
• Acute exacerbation of COPD
• Catheter-associated UTI - (specialist input)
  • Non-pregnant women and men aged 16 years and over with upper UTI symptoms
  • Children and young people aged 3 months to 16 years
• Pyelonephritis (acute) - (specialist input)
  • Non-pregnant women and men aged 16 years and over
  • Children and young people aged 3 months to 16 years
• Facial cellulitis - (first line)
• Bites (animal or human) - (first line)
• Lacerated wounds - (first line)

5.1.1.4 Antipseudomonal penicillins

Tazocin

(Piperacillin with tazobactam)

• Powder for solution for infusion 2g/250mg, 4g/500mg

Timentin

(Ticarcillin with clavulanic acid)

• Powder for solution for infusion 3g/200mg

Notes

1. For use within University Hospitals Plymouth NHS Trust

5.1.1.5 Mecillinams

Pivmecillinam

• Tablets 200mg (£5.40 = 10 pack)

Indications

• UTI (lower) in adults
  • Non-pregnant women and men aged 16 years and over
• Community multi-resistant UTIs
• Catheter-associated UTI
  • Non-pregnant women and men aged 16 years and over with no upper UTI symptoms