Formulary

5.1.13 Urinary-tract infections

First Line
Second Line
Specialist
Hospital Only
Nitrofurantoin
  • Modified-release capsules 100mg (£9.50 = 14 pack)
  • Tablets 100mg (£9.21 = 28 pack)
  • Oral suspension sugar free 25mg/5ml (£466.99 = 300ml bottle)

Indications

Notes

  1. Nitrofurantoin suspension is significantly more expensive than tablets and capsules, and should be avoided unless other options are not appropriate
  2. Catheter must be removed prior to treatment and not reinserted
Fosfomycin
  • Sachets 3g (£4.86 = 1 sachet)
  • Injection 2g, 4g

Indications

Notes

  1. Doses should be taken preferably before bedtime and after emptying the bladder
Methenamine hippurate
  • Tablets 1g (£14.89 = 60 tablets)

Indications

Notes

  1. Methenamine hippurate is to be considered after alternative formulary options have been used or if they are not suitable
  2. Methenamine hippurate requires an acidic urine for its antimicrobial activity - specialists will advise patients how to maintain acidic urine
  3. Avoid if eGFR less than 10mL/minute/1.73 m2 – risk of hippurate crystalluria