Trimethoprim

• Tablets 100mg (£0.97 = 28 tablets), 200mg (£1.87 = 14 tablets)
• Oral suspension sugar free 50mg/5ml (£4.12 = 100ml)

Indications

• Prostatitis (acute)
• Chronic Pelvic Pain Syndrome - (first line)
• UTI (lower) in children and young people aged 3 months to 16 years - (first line)
• Pyelonephritis (acute) – (specialist input)
  • Non-pregnant women and men aged 16 years and over
• Catheter-associated UTI (see note 2)
  • Non-pregnant women and men aged 16 years and over with no upper UTI symptoms - (first line)
  • Non-pregnant women and men aged 16 years and over with upper UTI symptoms – (specialist input)
  • Children and young people under 16 years - (first line)
• Moderate to severe acne:
  • Adults/ children and young people over 12 years - plus Epiduo OR Azelaic acid (off-label)

Notes

1. Trimethoprim may be considered or advised by specialists in pregnancy
   1. It is recommended that women who need to take trimethoprim during the first trimester also take high dose folic acid (5mg daily) until week 12 of pregnancy.
   2. Avoid trimethoprim if the woman has a low folate status or is on a folate antagonist (e.g. antiepileptic or proguanil).
2. Catheter can be changed or remain in situ.

Co-trimoxazole

• Tablets 80mg/400mg (£1.68 = 28 tablets)
• Oral suspension sugar free 40mg/200mg/5ml (£11.86 = 100ml)
• Oral suspension 80mg/400mg/5ml (£13.55 = 100ml)
• Solution for infusion ampoule 80mg/400mg/5ml (must be diluted in sodium chloride 0.9% or glucose 5% - seek advice) (£4.72 = 1 ampoule)

Notes

1. CSM recommends that co-trimoxazole should be limited to treatment and prevention of pneumocystis pneumonia.